Results: Insta-Your-Cells 2025/2026

Image 01

The Hungry Macrophage 

A CAR-macrophage (green) extending pseudopodia to engulf a tumor cell (red-labeled), capturing the moment of immune surveillance and phagocytosis in action. 

Image 02

Cosmic Colony 

Induced pluripotent stem cell (iPSC) colonies stained for nuclear (blue) and membrane-associated (red) markers, forming dense clusters that resemble a starry night sky. 

Image 03

Emerald Edge 

Human iPSC colony with nuclei stained blue and pluripotency marker highlighted in green, showing the vibrant growth and sharp boundary characteristic of undifferentiated stem cells. 

Image 04

Undifferentiated Love 

Immunocytochemistry of iPSCs stained for SSEA-3. Overlap of transmitted light, DAPI, Texas red is shown. Images were taken at 10x magnitude. The scale bar is 40 

Image 05

Hungry cell eats the mitochondria 

Endothelial cells expressing mt-mKeima were starved for 2 h. Lysosomal-localized mitochondria appear green, indicating mitophagy, while the intact mitochondrial network in the cytosol is shown in red. 

Image 06

Saturday Night Fibrosis 

Ovarian cancer and fibroblast coculture: α-SMA (magenta) marks contractile fibers, FAP (yellow) shows activity, and nuclei (cyan) shimmer like disco lights. An 80s-style dance floor where fibroblasts choreograph remodeling, invasion and resistance. 

Image 07

The Great ECM-Barrier Reef 

Fibroblasts, keratinocytes, and macrophages form a living reef: vimentin (green) shapes the scaffold, keratinocyte nuclei cluster like coral and macrophages (red) move like fish. This vibrant ecosystem reveals matrix–immune crosstalk in fibrosis. 

Image 08

Lung alveolar organoid 

Confocal microscopy of mouse alveolar organoid. AT2 cells with td tomato reporter grown in Matrigel. PRO-SPC, an AT2 marker(green) and AGER, an AT1 differentiation marker (white).  

Image 09

Lung on a dish 

Confocal microscopy of mouse alveolar organoid. AT2 cells with td tomato reporter grown in Matrigel. PRO-SPC, an AT2 marker(green) and AGER, an AT1 differentiation marker (white).  

Image 10

Multifaceted Guardians of Inflammation 

Different morphologies of murine macrophages reveal the plasticity of these immune cells, capable of driving both inflammation and tissue repair. Airyscan image acquired with a ZEISS Celldiscoverer 7 confocal microscope. 

Image 11

Mesenchymal Stem Cells Dancing on Microcarriers 

Mesenchymal stem cells spreading across microcarriers, forming the foundation of future tissue engineering breakthroughs. Each spindle-shaped cell tells a story of adaptability, resilience, and hope for scalable regenerative. 

Image 12

Dance of Death: NK Cell Strikes a Raji Cell 

Airyscan max-projection of an NK cell (YTS) and Raji cell conjugate imaged using a 63x/1.4 oil lens on a Zeiss LSM-800 confocal laser scanning microscope. Blue (Raji cell), Magenta (F-actin), cyan (perforin), Yellow (α-tubulin). 

Image 13

Cytotoxic Encounter: NK Cell-Mediated Lysis of a Raji Cell 

Airyscan max-projection of a multi-NK cell (YTS) and Raji cell conjugate imaged using a 63x/1.4 oil lens on a Zeiss LSM-800 confocal laser scanning microscope. Blue (Raji cell), Magenta (F-actin), cyan (perforin), Yellow (α-tubulin). 

Image 14

3D CAR-T Killing Assay 

The image is of Human STEAP1-IL18 CAR-T cells (Blue) in a co-culture 3D spheroid killing assay against target A549 cells (Green). Dying cells are stained Red. Cultures where under TME conditions (low oxygen and high hydrostatic pressure). 

Image 15

The colours of complexity 

Mesenchymal stem/stromal cell spheroids show high complex network formation capacity by expressing high levels of the pericytic marker CD146 (green) and MSC-related marker CD90 (red). 

Image 16

Chondrogenic differentiation of Love 

This is a chondrogenic differentiation of a primary cell culture of human mesenchymal stem cells derived from amniotic membrane. This was performed using Stem Pro (Gibco) Tri-lineage differentiation kit assay and Alcian Blue staining (Sigma Aldrich) 

Image 17

Symmetry in Asymmetry - a bipolar cell emerges on a dish 

Human iPSCs differentiated under adherent conditions produced retinal neurons, including rod bipolar cells. Immunofluorescence showed strong PKC alpha (green) in cell bodies and dendrites; DAPI (blue) labeled nuclei. PKCa aids rod signal transduction 

Image 18

Breathing boundaries - cilia in harmony with tight junctions 

Human iPSC-derived airway cells at air-liquid interface resemble proximal lung tissue, forming an epithelial barrier. ZO1 (green) marks tight junctions, ARL13B (red) labels cilia, and DAPI (blue) stains nuclei. ARL13B is key in cilium function. 

Image 19

Tubulin tidings - Pathways to Parkinson's repair 

Neuronal cells from human iPSCs show Beta-III tubulin (green) in the cytoplasm and extending into neurites and axons, marking them as immature neurons. DAPI (blue) stains nuclei, highlighting all cells in the field. 

Image 20

Cell that can help breathe in bloom 

Immunofluorescence shows iPSC-derived distal cells co-expressing SP-C (green) and nuclear SOX2, indicating a progenitor-like alveolar epithelial population with potential for self-renewal or repair, suggesting successful differentiation. 

Image 21

The signature of night vision - Rod opsin in a dish 

iPSC-derived neural retina cultures stained for rhodopsin (green) and DAPI (blue) showed abundant rod cells with elongated shapes and outer segments, radiating from an optic cup-like structure, reflecting typical rod-rich retinal organization. 

Image 25

Human Placenta-Derived Mesenchymal Stem Cells at Passage 1 

Phase-contrast image (20x) showing post-thaw expansion of human placenta-derived MSCs. Cells exhibit the classic spindle morphology and alignment pattern characteristic of viable, proliferative stem cells in early passages. 

Image 26

The hidden Landscape of the Kidney 

AFM topography of a renal glomerulus (100 × 100 µm) acquired with a 2 nm tip radius. This high-resolution image reveals the intricate surface morphology and biomechanical complexity of the glomerular structure, exposing its hidden 3D landscape. 

Image 27

The Cellular Maze of the Kidney 

AFM topography of a renal glomerulus (100 × 100 µm) captured with a 2 nm tip radius. The labyrinth of ridges and cavities highlights the microarchitecture and biomechanical complexity of the kidney’s filtration unit, vital for its function. 

Image 28

Papa was a Rolling Stone 

Humane AML cells (red+green) and humane CAR-NK cells (red) in mouse liver. Nucleii stained with DAPI. 

Image 29

The Black Hole 

Humane AML cells (red+green) and humane CAR-NK cells (red) in mouse liver. Nucleii stained with DAPI. 

Image 30

Tube formation/network development 

High-quality in vitro angiogenesis model image typically showing endothelial cells seeded on GelMA.Over 24 hours, cells align and migrate, forming interconnected, capillary-like tubular 

Image 31

In vitro angiogenesis 

vascular branching often follows principles of optimal geometry and minimal energy cost, resulting in symmetric or slightly asymmetric bifurcations. 

Image 32

Dopaminergic neurons in vitro 

Human pluripotent stem cell-derived dopaminergic neurons cultured in vitro for 45 days 

Image 33

Allogenic iPSC Derived RPEs for Treatment of AMD 

Human iPSC-derived Retinal Pigment Epithelial (RPE) Cells at 40 days maturity; image gallery is of dividing cells as collected 500 microseconds post-sort on a MACSQuant Tyto Lux cell sorter and large cell cartridge (LCC). 

Image 34

Forget spinach! This CAR-T got its iron boost from T-CellAmp and it is lit with killer power 

T-CellAmp from Ergon Pharmaceuticals elevates mitochondrial iron (green fluorescence) in CD8+ CAR-Ts, boosting proliferative and cytotoxic potential. The greener the CAR-T, the deadlier the cell. Green:iron; Red: mitochondria; Blue:nucleus. 

Image 35

Characterisation of a serial killer: what lies beneath the surface 

Confocal microscopy image of a Human CAR T-cell showing surface CAR receptor expression in magenta and internalized CAR receptors in green, with the chromosomes in metaphase shown in blue. 

Image 36

Characterisation of a serial killer: what lies beneath the surface 

Confocal microscopy image of a Human CAR T-cell showing surface CAR receptor expression in magenta and internalized CAR receptors in green, with the chromosomes in metaphase shown in blue. 

Image 37

hiPSC-derived RGCs transplanted in bovine retinal explant 

The confocal image shows hiPSC-derived RGCs expressing TdTomato, 7 days after transplantation into a bovine retinal explant. Bovine explants were stained with Human Nuclei (green) to identify the donor RGCs and Hoechst (blue) to visualize all nuclei. 

Image 38

hiPSC-derived RGCs transplanted in bovine retinal explant 

The confocal image shows hiPSC-derived RGCs expressing TdTomato, 7 days after transplantation into a bovine retinal explant. Bovine explants were stained with Human Nuclei (green) to identify the donor RGCs and Hoechst (blue) to visualize all nuclei. 

Image 39

hiPSC-derived RGCs transplanted in bovine retinal explant 

The confocal image shows hiPSC-derived RGCs expressing TdTomato, 7 days after transplantation into a bovine retinal explant. Bovine explants were stained with Human Nuclei (green) to identify the donor RGCs and Hoechst (blue) to visualize all nuclei. 

Image 40

Anchors of Motion: Paxillin and Actin Cytoskeleton in WJ-MSCs 

Phalloidin (green) marks actin filaments, paxillin (red) highlights focal adhesions, and DAPI (blue) stains nuclei, revealing the cytoskeletal organization and adhesion dynamics of Wharton’s Jelly MSCs. 

Image 41

Anchors of Motion: Paxillin and Actin Cytoskeleton in WJ-MSCs 

Phalloidin (green) marks actin filaments, paxillin (red) highlights focal adhesions, and DAPI (blue) stains nuclei, revealing the cytoskeletal organization and adhesion dynamics of Wharton’s Jelly MSCs. 

Image 42

Filaments of Identity: Vimentin Expression in AM-MSCs 

Vimentin (red) defines the intermediate filament network, while DAPI (blue) stains nuclei, illustrating the characteristic mesenchymal architecture of amnion-derived mesenchymal stem cells. 

Image 43

Oil Red O Staining of Differentiated PDL-MSCs 

Oil Red O staining shows lipid droplet accumulation in periodontal-ligament–derived mesenchymal stem cells, confirming their adipogenic differentiation potential. 

Image 44

Immunofluorescence co-staining of focal adhesions and F-actin colocalization in periodontal ligament derived-MSCs-60X 

Immunofluorescence co-staining with paxillin (focal adhesions-red), F-actin (phalloidin-green) & nucleus (DAPI-blue) in periodontal ligament derived mesenchymal stem cells (PDL-MSCs) images-60X magnification using NIKON confocal microscope. 

Image 45

Immunofluorescence staining of non-muscle myosin IIA in periodontal ligament derived-MSCs-60X 

Immunofluorescence staining of non-muscle myosin IIA (Red) and nucleus (DAPI-blue) in PDL-MSCs images-60X magnification using NIKON confocal microscope.   

Image 46

Immunofluorescence co-staining of focal adhesions and F-actin colocalization in periodontal ligament derived-MSCs-60X 

Immunofluorescence co-staining with paxillin (focal adhesions-red), F-actin (phalloidin-green) & nucleus (DAPI-blue) in periodontal ligament derived mesenchymal stem cells (PDL-MSCs) images-60X magnification using NIKON confocal microscope. 

Image 47

Immunofluorescence staining of vimentin (Red) in amniotic membrane derived-MSCs-60X 

Immunofluorescence staining of vimentin (Red) and nucleus (DAPI-blue) in AM-MSCs images-60X magnification using NIKON confocal microscope. 

Image 48

Immunofluorescence staining of F-actin in periodontal ligament derived-MSCs-60X 

Immunofluorescence staining with F-actin (phalloidin-green) & nucleus (DAPI-blue) in periodontal ligament derived mesenchymal stem cells (PDL-MSCs) images-60X magnification using NIKON confocal microscope.   

Image 49

Stromal Cell Portraits: Visualized by Cell Painting 

This image demonstrates how our group conducts mesenchymal stromal cell morphological profiling via Cell Painting. Stains for the actin cytoskeleton, mitochondria, endoplasmic reticulum, and nucleus capture the complex intracellular state of MSCs. 

Image 50

Orbital Strike 

CAR-T cells clustering around a tumor spheroid in a microfluidics chip, colored in time. (Color scheme 1) 

Image 51

Purple People Eater 

CAR-T cells clustering around a tumor spheroid in a microfluidics chip, colored in time. (Color scheme 2) 

Image 52

Meteor Shower 

Traces of CAR-T cells approaching a solid tumor spheroid in a microfluidics chip, colored in time. 

Image 53

End of the Rainbow 

Traces of CAR-T cells approaching a solid tumor spheroid in a microfluidics chip, colored in time. 

Image 54

Human Oligodendrocyte Monolayer 

Human mature oligodendrocyte 2D monolayer generated using the H1 human embryonic stem cells using the Douvaras and Fossati, 2015 protocol. 120 days into the protocol, the oligodendrocytes express CNPase 488, MYRF 555 & phaloidin 647. Blue is DAPI. 

Image 55

Human Cerebral Organoids 

Human 3D cerebral organoids generated using PGP1 induced pluripotent stem cells. At 60 days, the organoids display neuroepithelia with a ventricular zone lined by ZO1+ 488 apical membrane & a cortical plate with TBR1+ 555 neurons. Blue is DAPI. 

Image 56

Born to Remember 

Hippocampal neurons branded by fate—ZBTB20 shines green alongside PROX1, marking cells programmed for memory formation. iPSC-derived organoids prove we can recreate the brain's most enigmatic region, one trancription factor at a time. 

Image 57

Neural Highways 

iPSC-derived cortical neurons weave intricate networks visualized through MAP2AB and GFAP markers. Confocal imaging captures the architectural marvel of interconnected pathways—where neurons and glia collaborate to build the brain's communicationgrid 

Image 58

Astrocyte Supernova 

Cortical organoid erupting with GFAP-positive astrocytes, captured in Cy3's amber glow. This iPSC-derived structure demonstrates the remarkable self-organizing capacity of brain tissue, where glial networks radiate outward to support neural circuits 

Image 59

Virtual Cell 

The virtual cell digitally replicates how real cells behave, using AI and omics data to design small molecules that precisely control cell functions—accelerating biomanufacturing, regenerative medicine, and cell therapy innovation. 

*This image is AI-generated.*

Image 60

A Colony Called Love 

This image shows a clonogenic colony derived from human mesenchymal stem cells (hMSCs) isolated from umbilical cord tissue. The colony displays a compact, well-defined morphology and a distinctive heart-shaped structure, indicative of the high prolif 

Image 61

The impressionist gardern of Nature 

Immunofluorescence of a rat brain section exposed to hyperoxia as a model of bronchopulmonary dysplasia. 8-oxo-dG, a marker of DNA oxidation, was detected in red, GFAP, a marker of astrocytes, was detected in purple, and TUJ1 in green. 

Image 62

The Secret Life of Cells: Neon Edition 

Human alveolar epithelial cells exposed to hydrogen peroxide damage, labelled in red for Ki67 and in green for DNA oxidation with 8-oxo-dG antibody. Nuclei are stained blue. 

Image 63

Neural Constellations 

Immunofluorescence of a rat brain section exposed to hyperoxia as a model of bronchopulmonary dysplasia. In red is stained Nrf2. Red dots indicate Nrf2 translocated into the nucleus to perform its function as a transcription factor, in green Keap1. 

Image 64

The gut aurora 

“The Gut Aurora”. Confocal image of a mouse colon organoid (20x magnification). Nuclei are stained with DAPI (blue), proliferating cells with Ki67 (magenta), and actin filaments with phalloidin (green). 

Image 65

Engineering Immunity, One Particle at a Time. 

AI-generated depiction of a chimeric antigen receptor (CAR) T cell surrounded by viral and lipid nanoparticles. 

*This image is AI-generated.*

Image 66

3D CytoNicheL: MSCs Bloom & Boom！

Mesenchymal Stem Cells (MSCs) cultured in a three-dimensional (3D) system. The image illustrates that MSCs effectively anchored to the surface and internal pores of the 3D microcarriers, followed by vigorous and rapid proliferative activity.

Image 67

A Cellular Red Carpet

Mesenchymal stem cells (MSCs) enter their own “hall of fame” in this vibrant red-carpet scene. The actin cytoskeleton (phalloidin staining in red and green) reveals the dynamic organization of cocultured MSCs, captured with a ZEISS confocal microscope. The blue nuclei highlight their collective choreography—an elegant dance of regeneration and structure.

Image 68

What a Nephron!

Stereomicroscope and phase-contrast images illustrate spontaneously formed tubule-like structures arising from mixed populations of urine-derived renal stem/progenitor cells and CD133⁻ cells, exhibiting morphological features comparable to nephrons.

Image 69

Lights, Cells, Action! uARPC Spheroids Show Their True Colors

Expression of stem cell markers in renal stem/progenitor cells (RPC) spheroids: whole-mount double-label immunofluorescence shows that RPC spheroids expressed high levels of the functional and constitutional marker CD133 and of beta-actin.

Image 70

The Stem Cell Groove: Spontaneous Morphogenesis in CD133/SSEA4 Spheroids

Spheroids, derived from renal stem/progenitor cells (RPC), coexpressing the CD133 and SSEA4 markers, can spontaneously form the typical groove of organoids.

Image 71

Loss of muscle integrity in human heart cells 

Confocal image at 60X of human iPSC-derived cardiomyocytes under hypoxia. Troponin-T (Red), apoptotic cell(Yellow), nuclei (cyan) 

Image 72

Apoptotic cardiomyocyte 

Confocal image at 60X of human iPSC-derived cardiomyocytes. Troponin-T (Red), apoptotic cell(Yellow), nuclei (cyan). 

Image 73

Green pluripotent stem cells 

human iPSC colony expression PRG4-GFP reporter post electroporation 

Image 74

Green pluripotent stem cell 

human iPSC single cell expressing PRG4-GFP reporter post electroporation 

Image 75

Healthy and apoptotic cluster of cardiomyocyte in proximity 

Confocal image of human iPSC-derived cardiomyocytes. Showing healthy and apoptotic cluster of cardiomyocytes. Troponin-T (Red), apoptotic cell(Yellow), nuclei (cyan). 

Image 76

Uptake of CD19 CAR-EVs by PBMCs 

EVs from CD19 CAR-T cells (CD34 hinge, CD28 TM/co-stim, ζ-NeonGreen) are internalized by PBMCs; NeonGreen and CD34-PE signals colocalize in cytoplasm and at membrane (CellMask), supporting CAR cargo transfer without lentiviral vectors. 

Image 77

Spiky Heart of Strength 

The image showcases a 3D model of tibia trabecular bone sculpted into a heart shape! Trabecular bone in the tibia is like nature's own latticework – a mesh of trabeculae optimized for load-bearing efficiency while minimizing bone mass.

Image 78

Stem cell and extracellular matrix "roots" 

Picture of a mesenchymal/stromal stem cell surrounded by extracellular matrix from a human amniotic membrane under scanning electron microscopy 

Image 79

Constellation 

Immunofluorescence of prostate cancer cells (PC3) stained with DAPI (blue), phalloidin (red), and SRXN1 protein (green).

Image 80

A life bomb 

Immunofluorescence of a prostate cancer cell during the cell division process, stained with DAPI (blue) and Ki67 (red).